CellASIC Microfluidic Plates
   

The general principle behind CellASIC microfluidic plates is to create application specific devices for cell culture research and screening.

Currently available application specific microfluidics are listed in the Products page. For suggestions of new designs, please contact info@cellasic.com.

Standard 96 Well Plate Format

Our microfluidic components are formatted to a standard 96 well plate frame. Samples are dispensed directly into the wells, preventing headaches caused by air bubbles, priming, and tube connections.

   
   

Data Collection

The preferred method of cell interrogation is with an inverted microscope, due to the superior optical qualities of the microfluidic plate. The microfluidic layer is composed of a transparent silicone elastomer with the bottom surface of a #1.5 thickness borosilicate cover glass.

 
Microfluidic Perfusion Cell Culture
 
CellASIC is dedicated to advancing the state-of-the-art for microfluidic cell culture technology. The scientific team has been involved in numerous advances in this arena, dating back to 2003. We strive to be a leader in this field by combining our unique expertise in engineering, product development, and cell biology. We have benefited significantly from scientific collaboration, typically with biologists with specific applications. Please email us (info@cellasic.com) for further information about collaboration and custom fabrication.
 
Publication List:
  1. “A Microfluidic System for Dynamic Yeast Cell Imaging.” Biotechniques, 2008
  2. “Microfluidic Environment for High Density Hepatocyte Culture.” Biomedical Microdevices, 2008
  3. “Microfluidic System for Automated Cell-based Assays.” Journal of the Association of Laboratory Automation (JALA), 2007
  4. “Microfluidic Tissue Model for Live Cell Screening.” Biotechnol Prog. 2007
  5. “An Artificial Liver Sinusoid with a Microfluidic Endothelial-like Barrier for Primary Hepatocyte Culture.” Biotechnol Bioeng. 2007
  6. “Microfluidics-based Systems Biology.” Molecular Biosystems, 2006
  7. “Nanoliter Scale Microbioreactor Array for Quantitative Cell Biology” Biotechnology & Bioengineering, 2006
  8. “Microfluidic Alignment of Collagen Fibers for in vitro Cell Culture.” Biomedical Microdevices, 2006
  9. “Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs.” Appl. Phys. Lett. 2005
  10. “Continuous Perfusion Microfluidic Cell Culture Array for High-Throughput Cell-Based Assays.” Biotechnology & Bioengineering. 2005
  11. “A Novel High Aspect Ratio Microfluidic Design to Provide a Stable and Uniform Microenvironment for Cell Growth in a High Throughput Mammalian Cell Culture Array” Lab Chip. 2005
  12. “On-chip cell lysis by local hydroxide generation”, Lab Chip, 2005

  13. “The role of cell morphology in alkaline hemolysis”, Cytometry A, 2005
  14. “Microfabricated suspensions for electrical connections on the tunable elastomer membrane”, Appl. Phys. Lett., 2004